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Our directory of funded grants

7 result(s) found

A national coordinating neuroinformatics framework for autism and related conditions

Project Overview

New approaches in neurodevelopmental research increasingly seek to integrate enormous amounts of data through sophisticated informatics so as to determine the relationship between genotype and phenotypes, both structural and functional, as they change over time during development. Such approaches dw…

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Principal Investigator:
  • Alan Evans, Montreal Neurological Institute and Hospital, McGill University
Team Members:
  • Mayada Elsabbagh, McGill University
  • Sébastien Jacquemont, Sainte-Justine University Hospital Research Centre
  • Guy Rouleau, Montreal Neurological Hospital and Institute
  • Stephen Scherer, The Hospital For Sick Children
  • Peter Szatmari, Centre for Addiction and Mental Health
  • Evdokia Anagnostou,

    Holland Bloorview Kids Rehabilitation Hospital

  • Teresa Bennett, McMaster University
  • Bruce Pike, Montreal Neurological Hospital and Institute
  • Laurent Mottron, Université de Montréal

Co-clinical trials in mice and humans in autism

Project Overview

Autism has many causes, yet no single cause explains why many children and adults have autism. This makes treating the symptoms of autism difficult, since how somebody responds to treatment might depend on what cause autism in the first place. We thus need both better treatments and ways of figuring…

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Principal Investigator:
  • Evdokia Anagnostou,

    Holland Bloorview Kids Rehabilitation Hospital

Team Members:
  • Jason Lerch, University of Toronto
  • Jane Foster, McMaster University
  • Barry Greenberg, Krembil Research Institute
  • Robert Nicolson, University of Western Ontario
  • Teresa Bennett, McMaster University
  • Rosanna Weksberg, The Hospital For Sick Children
  • Stephen Scherer, The Hospital For Sick Children

Correction of Neuronal Function in Autism

Project Overview

The prevalence of autism spectrum disorders (ASDs) is rising dramatically on a yearly basis and new interventional strategies are required to treat ASDs and related disorders like Fragile X syndrome. Altered communication between brain cells may lead to the defects responsible for the features that …

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Principal Investigator:
  • Laurie Doering, McMaster University
Team Members:
  • Min Zhuo, University of Toronto
  • Ali Pejmun Haghighi, McGill University
  • David Nelson, Baylor College of Medicine

Mouse brain imaging for neurodevelopmental disorders

Project Overview

The project provides state of the art mouse brain imaging to researchers in Canada working on models of neurodevelopmental disorders. The use of mouse models enables scientists to probe the function of the multiple genes implicated in neurodevelopmental disorders. Our ability to characterize the phe…

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Principal Investigator:
  • Jason Lerch, University of Toronto

Novel approaches to early detection and treatment of ASD

Project Overview

More than 1 in 100 individuals are diagnosed with Autism Spectrum Disorder (ASD), with profound impacts on the quality of life of those who are affected and their families. Until recently, children were rarely referred for assessment before age 2, so we knew little about ASD early in life. Prior stu…

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Principal Investigator:
  • Lonnie Zwaigenbaum, University of Alberta
Team Members:
  • Ofer Golan, Bar-Ilan University
  • Jessica Brian, Holland Bloorview Kids Rehabilitation Hospital
  • Sam Wass, MRC Cognition and Brain Sciences Unit
  • Mark Johnson, CBCD, Birkbeck, University of London
  • Susan Bryson, IWK Health Centre
  • Isabel Smith, IWK Health Centre
  • Azadeh Kushki, IWK Health Centre